• For diabetic macular edema (DME)
  • For macular edema following branch retinal vein occlusion (BRVO)
    or central retinal vein occlusion (CRVO)
  • For noninfectious posterior segment uveitis

OZURDEX® TARGETS MULTIPLE

INFLAMMATORY CYTOKINES

  • OZURDEX® is a sustained-release, biodegradable steroid implant containing dexamethasone, a corticosteroid4
  • Dexamethasone has been shown to suppress inflammation by inhibiting multiple inflammatory cytokines, resulting in decreased4:
  • Edema 
  • Fibrin deposition
  • Capillary leakage
  • Migration of inflammatory cells

SEE HOW OZURDEX® WORKS TO TREAT

DIABETIC MACULAR EDEMA (DME)

SEE 3-YEAR CLINICAL EFFICACY

GO

SEE HOW OZURDEX® WORKS TO TREAT

MACULAR EDEMA FOLLOWING RVO

(BRVO OR CRVO)

HOW OZURDEX® WORKS IN

NONINFECTIOUS POSTERIOR

SEGMENT UVEITIS

  • Dexamethasone, a corticosteroid, has been shown to suppress inflammation by inhibiting multiple inflammatory cytokines resulting in decreased edema, fibrin deposition, capillary leakage, and migration of inflammatory cells4
  • In noninfectious posterior segment uveitis, evidence suggests that inhibition of the cytokine NF-kB plays a key role in suppression of inflammation7

NOVADUR® TECHNOLOGY:

A PROPRIETARY DRUG DELIVERY SYSTEM

  • A sustained-release, biodegradable steroid implant4
  • Solid polymer matrix contains 0.7 mg of dexamethasone, a corticosteroid4
  • Biodegrades to lactic acid and glycolic acid4
  • Administered by injection as an in-office procedure4

Tiny

implant

Before

implantation

3 weeks

after implantation

 

Scanning electron microscopy (SEM) magnification of implant surface in an animal model. Clinical significance unknown.3

A PATENTED

INTRAVITREAL APPLICATOR

  • Sterile, single-use applicators are supplied preloaded with an implant4
  • Includes second-generation needle
  • Implants are administered using a shelved injection technique4

SEE HOW THE OZURDEX®

APPLICATOR WORKS

Click here to access injection technique educational resources.

HELP PATIENTS LEARN MORE ABOUT OZURDEX® FOR THEIR CONDITION